منابع مشابه
Redox biochemistry of hydrogen sulfide.
H(2)S, the most recently discovered gasotransmitter, might in fact be the evolutionary matriarch of this family, being both ancient and highly reduced. Disruption of gamma-cystathionase in mice leads to cardiovascular dysfunction and marked hypertension, suggesting a key role for this enzyme in H(2)S production in the vasculature. However, patients with inherited deficiency in gamma-cystathiona...
متن کاملThe Redox Biochemistry of Hydrogen Sulfide
H2S, the most recently discovered gasotransmitter, might in fact be the evolutionary matriarch of this family, being both ancient and highly reduced. Disruption of γ-cystathionase in mice leads to cardiovascular dysfunction and marked hypertension, suggesting a key role for this enzyme in H2S production in the vasculature. However, patients with inherited deficiency in γcystathionase apparently...
متن کاملThe redox biochemistry of protein sulfenylation and sulfinylation.
Controlled generation of reactive oxygen species orchestrates numerous physiological signaling events (Finkel, T. (2011) Signal transduction by reactive oxygen species. J. Cell Biol. 194, 7-15). A major cellular target of reactive oxygen species is the thiol side chain (RSH) of Cys, which may assume a wide range of oxidation states (i.e. -2 to +4). Within this context, Cys sulfenic (Cys-SOH) an...
متن کاملExercise redox biochemistry: Conceptual, methodological and technical recommendations☆
Exercise redox biochemistry is of considerable interest owing to its translational value in health and disease. However, unaddressed conceptual, methodological and technical issues complicate attempts to unravel how exercise alters redox homeostasis in health and disease. Conceptual issues relate to misunderstandings that arise when the chemical heterogeneity of redox biology is disregarded: wh...
متن کاملRefocusing Generalised Normalisation
When defined with general elimination/application rules, natural deduction and λ-calculus become closer to sequent calculus. In order to get real isomorphism, normalisation has to be defined in a “multiary” variant, in which reduction rules are necessarily non-local (reason: nomalisation, like cut-elimination, acts at the head of applicative terms, but natural deduction focuses at the tail of s...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nature Chemical Biology
سال: 2008
ISSN: 1552-4450,1552-4469
DOI: 10.1038/nchembio0508-267